Rumored Buzz on EAM-2201
Rumored Buzz on EAM-2201
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The purpose of the research will be to characterize the metabolites of EAM-2201 in human hepatocytes attained in vitro and those in liver and urine specimens obtained in vivo through the autopsy of the EAM-2201 abuser.
Twelve metabolites of a artificial cannabinoid, EAM-2201, were being tentatively discovered in human hepatocytes in vitro, and in human liver and urine specimens in vivo for the first time. There was a definite variance in metabolism profile involving the in vitro and in vivo outcomes.
EAM-2201 was incubated with human hepatocytes for three h in a very CO2 incubator as well as the metabolites of EAM-2201 were generated. The human liver specimen was homogenized along with the metabolites were extracted. The urine specimen was hydrolyzed initially with β-glucuronidase and also the metabolites were being extracted.
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